Practically speaking, no. This post goes into detail as to the reasons why.
While a person can use the things to generate electricity, they’re even more hideously inefficient at doing that they they are at moving heat. Roughly speaking, it’d take about 100 watts worth of heat to end up with one of electricity. That may be good enough for plutonium-powered space probes, but there are very few applications on the surface of the earth where their use makes sense compared to the alternatives.