The difference between RNL/RNQ and RL/RQ from FTDI’s ICs may not be apparent at first glance.
Confirmed by FTDI, these two numbers are both the same in performance and specifications. The only difference is the fab location.
Unfortunately, there is no PCN for fab location change since there are no changes to the physical design of the chip or package.
For example, see below comparison table for the part numbers FT232RNL-REEL and FT232RL-REEL:
Currently, FT232RL/RQ chips are Not For New Designs (NRND). We do not know when the RL/RQ chips will become available again.
Applicable Part numbers
768-FT232RNL-REELTR-ND,768-FT232RNL-REELCT-ND,768-FT232RNL-REELDKR-ND
768-FT245RNQ-TRAY-ND
768-FT245RNL-REELTR-ND,768-FT245RNL-REELCT-ND,768-FT245RNL-REELDKR-ND
768-FT245RNL-TUBE-ND
768-FT245RNQ-REELTR-ND,768-FT245RNQ-REELCT-ND,768-FT245RNQ-REELDKR-ND
768-1008-2-ND,768-1008-1-ND,768-1008-6-ND
768-1012-2-ND,768-1012-1-ND,768-1012-6-ND
768-FT232RNQ-REELTR-ND,768-FT232RNQ-REELCT-ND,768-FT232RNQ-REELDKR-ND
768-1007-2-ND,768-1007-1-ND,768-1007-6-ND
768-1011-2-ND,768-1011-1-ND,768-1011-6-ND
768-1306-ND
768-1307-ND
768-1349-ND
768-FT232RNL-TUBE-ND
768-FT232RNQ-TRAY-ND
FT245RQ-TRAY-ND
FT232RNL-REEL
FT245RNQ-TRAY
FT245RNL-REEL
FT245RNL-TUBE
FT245RNQ-REEL
FT232RQ-REEL
FT245RQ-REEL
FT232RNQ-REEL
FT232RL-REEL
FT245RL-REEL
FT232RL-TUBE
FT232RQ-TRAY
FT245RL-TUBE
FT232RNL-TUBE
FT232RNQ-TRAY
FT245RQ-TRAY