yes, when we say: parametric equivalent, we are really talking about close to perfect matches as possible drop-in substitute of the whole series of Automotive, AEC-Q100, R²Coupler™ as OPTOISOLATOR 5kV TRANSISTOR from Broadcom Limited in all these cases: ACPL-K43T-060E vs ACPL-K43T-500E & ACPL-K43T-000E.
Please review the datasheets to ensure the alternative will work for your application.